AVM Biotechnology's COVID-19 treatment, a repurposed version of dexamethasone developed without the use of aborted fetal materialSEATTLE, WA, US, October 14, 2020 /EINPresswire.com/ -- There has been much criticism of the President who has openly decried the use of aborted fetal material in scientific research, for allowing Regeneron’s antibody product and remdesivir to be used in his COVID-19 treatment. Many are going so far as to call him a hypocrite since his administration banned the use of newly aborted fetal material in government funded research.
AVM Biotechnology’s lead investigational drug, AVM0703, for moderate to severe COVID-19 Acute Respiratory Distress Syndrome (ARDS) does not utilize aborted fetal or other ethically objectionable material in either the discovery, development, manufacture or testing of the drug.
There are several COVID-19 vaccines and treatments in development which are manufactured or tested utilizing aborted fetal material. People are seeking a treatment option with a positive safety profile that has no connection to fetal materials.
Seattle’s AVM Biotechnology is developing such a treatment. AVM0703 has FDA approval for clinical trials in both relapsed/refractory (R/R) Non-Hodgkin’s Lymphoma and ARDS caused by either COVID-19 or Influenza.
For those who cannot participate in one of these trials, AVM Biotechnology offers an Expanded Access (“Compassionate Use”) Program for AVM0703 https://avmbiotech.com/compassionate-use/ as well as template documents and guidance for treating physicians to facilitate the application process. AVM0703 can be considered for a single-patient, Physician-sponsored IND for Emergency/Expanded Use.
AVM0703 is a patent-pending, highly-concentrated form of injectable dexamethasone that, when given at suprapharmacologic doses, induces a rapid and striking immune response mediated by supercharged Natural Killer T cells. NKTs are programmed by nature to eliminate abnormal cells, whether cancer or virus-infected. NKTs also have the potential to trigger both antibody and T cell long-term immunity.
In addition to Regeneron and remdesivir, President Trump received NIH recommended daily low dose dexamethasone for his COVID-19 disease, highlighting the usefulness of dexamethasone, which has been widely used since its initial approval in 1958 in treating many chronic conditions. Although multiple generic versions of dexamethasone are available in the US, generic dexamethasone cannot be used at the suprapharmacologic doses necessary to induce the striking immune response of AVM0703, because excipients such as benzyl alcohol and/or parabens in the generic products then exceed safe levels.
AVM Biotechnology is led by its founder Dr. Theresa Deisher, a biotech veteran with a productive history including 47 patents and four discoveries in clinical trials. Its COO, Janet R. Rea, has a proven track record working with federal regulators and successfully bringing drugs to market. The Executive Board is comprised of world leaders in the areas of respiratory illness, regulatory affairs, and vaccine development, and AVM is guided by a global Advisory Board that includes well-respected leaders in the areas of cancer and immunology. The company has received two SBIR grants and holds eight worldwide patent families that cover the use and formulation of AVM0703 as well as three other AVM Biotechnology programs. The AVM team is committed to developing products that improve outcomes without additional suffering, because they believe side effects from treatments should never be worse than the diseases themselves.
Most importantly, AVM Biotechnology does not use any aborted fetal material in the discovery, development, or manufacture of any products. This commitment is a founding principle of the organization.
For additional information about the Compassionate Use Program, visit https://avmbiotech.com/compassionate-use/ or contact Jena Dalpez Jdalpez@avmbiotech.com.
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